With smaller teams, tighter cut-off times, and short, explosive stages, Tour sprinters find themselves off the back.
"Everything that could go wrong, did," said Etixx-Quick-Step boss Patrick Lefevere
Veteran leadout man Mark Renshaw ready to pilot Mark Cavendish to further 2015 success in Turkey
Mark Cavendish adds another victory to his 2015 tally with the win at the Clásica de Almería in Spain
Renshaw takes his first win in an Omega Pharma-Quick Step kit and moves into overall lead in Britain
Renshaw signed with Omega Pharma-Quick Step in the offseason after the riders were separated for two years
Caleb Ewan has drawn comparisons to the British speedster and will ride for Orica-GreenEdge this summer
Aussie is hunting victory in Alberta before returning to the side, or front wheel, of Mark Cavendish
Renshaw, Bos among the riders injured in a late crash at the Presidential Tour of Turkey
A crash in the last corner of Sunday's second Giro stage may prove difficult to overcome for Mark Renshaw and Theo Bos
After three stage wins at Turkey, Rabobank heads into Giro with leadout squad intact – and a wealth of confidence.