Riders throughout the peloton hold Tirreno-Adriatico in high regard as a key prep race for the Giro d'Italia and a prestigious prize.
The "Race of the Two Seas" kicks off Wednesday with a team time trial and runs through March 14.
Four top riders from The Netherlands will compete at the Italian grand tour in May.
Tom Dumoulin confirms intentions to pursue an overall win at a grand tour. The TT specialist proved his potential at the 2015 Vuelta.
Young Dutchman Tom Dumoulin may challenge perennial time trial favorite Tony Martin in Qatar at UCI world championships.
Tom Dumoulin critical of time trial rival Bradley Wiggins racing with TUE for corticosteroid
Time trial gold medal favorite Tom Dumoulin was given the all-clear to go to the Rio Olympics, just four days after fracturing his wrist
Tom Dumoulin crashes in Tour de France stage 19, injuring his wrist, putting a question mark over his Olympics participation.
Though he's focused on the 2016 Olympics, Dumoulin is ready to commit himself to his potential to win a grand tour after Tour de France
Focusing on stage wins over GC aspirations pays off for Tom Dumoulin