Chris Froome, Alberto Contador, and Alejandro Valverde can all ride into the record books at the Vuelta, which begins Saturday.
The Sky rider could become the first cyclist to win the Tour-Vuelta double in modern Vuelta history.
Vuelta a Burgos is an ideal training ground for the final grand tour of the season, the Vuelta, where Contador hopes to rebound with a win.
Alberto Contador returns to competition at Clásica San Sebastián, three weeks after crashing out of the Tour de France.
The Spaniard abandoned the Tour during Sunday's stage 9 following crashes in early days of the race.
Alberto Contador was no doubt disappointed to leave the Tour de France. But really, he should set his sights on other goals.
Multiple teams came to the Tour de France with more than one GC option, but potential conflicts have fizzled out.
Alberto Contador pulls out of the Tour de France with 100 kilometers left to race in stage 9
Alberto Contador's yellow jersey campaign is all but over after another rough day in the Tour
Alberto Contador has not won the Tour since 2009, and his hopes of winning this year's race have dwindled after crashes.