The "Race of the Two Seas" kicks off Wednesday with a team time trial and runs through March 14.
Britain's Adam Yates (Orica-Scott) won the GP Industria & Artigianato for the second time since 2014 on Sunday.
Esteban Chaves already has two grand tour podium finishes, and this summer he will shoot for another one in France.
After five seasons in the peloton, the Australia-based team has become a GC threat in grand tours and other stage races.
Esteban Chaves and the Yates twins, Adam and Simon, are all capable of winning a grand tour.
Simon and Adam, 24, will remain with the Australian outfit as they continue to improve on the road.
From Sky's dominance to another impressive performance by Peter Sagan, AFP breaks down the 103rd Tour.
White jersey Adam Yates is just one of many up-and-comers taking big steps forward in this year's Tour de France
Adam Yates has confidence after attacking Tour de France favorites in early stages. The Brit wants to claim a stage win.
Mavic neutral support moto captures the moment when Adam Yates crashes into the inflatable arch that collapsed at the Tour.