CSC's Fabian Cancellara held on to win the 43rd edition of the Tirreno-Adriatico following Tuesday's seventh and final stage.

Italian Francesco Chicchi of Liquigas won the 176km run around San Benedetto del Tronto.

But the 26-year-old Swiss, the current double world time-trial champion, kept hold of the leader's blue jersey and set himself up as one of the hot favorites for Saturday's Milan-San Remo.